Thrombopoietin receptor agonists: ten years later
نویسندگان
چکیده
منابع مشابه
Workcraft: Ten Years Later
A large number of models that are employed in the field of concurrent systems’ design, such as Petri nets, Signal Transition Graphs, gate-level circuits, dataflow structures have an underlying static graph structure. Their semantics, however, is defined using additional entities, e.g. tokens or node/arc states, which collectively form the overall state of the system. We jointly refer to such fo...
متن کاملMigratory Typing: Ten Years Later
In this day and age, many developers work on large, untyped code repositories. Even if they are the creators of the code, they notice that they have to figure out the equivalent of method signatures every time they work on old code. This step is time consuming and error prone. Ten years ago, the two lead authors outlined a linguistic solution to this problem. Specifically they proposed the crea...
متن کاملThe biology of thrombopoietin and thrombopoietin receptor agonists.
Thrombopoietin (TPO) is the major physiological regulator of platelet production. TPO binds the TPO receptor, activates JAK and STAT pathways, thus stimulating megakaryocyte growth and platelet production. There is no "sensor" of the platelet count; rather TPO is produced in the liver at a constant rate and cleared by TPO receptors on platelets. TPO levels are inversely proportional to the rate...
متن کاملComputability Closure: Ten Years Later
The notion of computability closure has been introduced for proving the termination of higher-order rewriting with first-order matching by Jean-Pierre Jouannaud and Mitsuhiro Okada in a 1997 draft which later served as a basis for the author's PhD. In this paper, we show how this notion can also be used for dealing with beta-normalized rewriting with matching modulo beta-eta (on patterns \`a la...
متن کاملClinical indications for thrombopoietin and thrombopoietin-receptor agonists.
Thrombocytopenia is a common hematologic disorder. Stimulation of thrombopoiesis may reduce the risk for thrombocytopenia-induced bleeding, prevent severe thrombocytopenia, and reduce the need for platelet transfusion. The key cytokine is thrombopoietin (TPO). It regulates proliferation and maturation of megakaryocytes as well as platelet production. TPO is synthesized in the liver. Development...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Haematologica
سال: 2019
ISSN: 0390-6078,1592-8721
DOI: 10.3324/haematol.2018.212845